The nucleic acid data:
IRESite Id: 38 Version: 7
Originaly submitted by: Václav Vopálenský Submission date: 2005-06-26 00:00:00
Reviewed by: Václav Vopálenský Last change: 2007-05-15 00:00:00
IRESite record type:
  natural_transcript
The shape of the nucleic acid molecule translated:
  linear
The quality of the mRNA/+RNA sequence:
  hopefully_full-length_mRNA
The abbreviated name of the virus/gene coding for this mRNA/+RNA molecule:
  GBV-A
The genetic origin of this natural mRNA/+RNA:
  viral
The GenBankId GI:# number of exactly this mRNA/+RNA sequence:
1572847
The mRNA/+RNA description: 
Hepatitis GB virus A polyprotein, complete cds.
The mRNA/+RNA sequence represented in the +DNA notation:


Credibility of mRNA sequence:
  guessed_as_the_sequence_was_never_published_by_authors_nor_described_in_sufficient_detail
The organism containing this mRNA with IRES segment in its genome:
Hepatitis GB virus A
A promoter reported in cDNA corresponding to IRES sequence:
  not tested
The total number of notable open-reading frames (ORFs):
  1
Notable Open-Reading Frames (ORFs; protein coding regions) in the mRNA/+RNA sequence:
ORF
ORF position:   1
Version: 1
Originaly submitted by: Václav Vopálenský Reviewed by: Václav Vopálenský
The abbreviated name of this ORF/gene:
GBV_A
The description of the protein encoded in this ORF:
Hepatitis GB virus A polyprotein.
The translational frameshift (ribosome slippage) involved:
  0
The ribosome read-through involved:
  no
The alternative forms of this protein occur by the alternative initiation of translation:
  no
The ORF absolute position (the base range includes START and STOP codons or their equivalents):
  594-9458
Remarks:
Monocistronic and bicistronic T7 transcripts were tested in vitro in rabbit reticulocyte lysates.
Citations:
Simons J. N., Desai S. M., Schultz D. E., Lemon S. M., Mushahwar I. K. (1996) Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization. J. Virol. 70(9):6126-6135
IRESs:
IRES:
Version: 8 Last change: 2007-05-15 00:00:00
Originaly submitted by: Václav Vopálenský Reviewed by: Václav Vopálenský
The IRES name:
  GBV-A
The IRES absolute position (the range includes START and STOP codons or their equivalents):
  15-707
Conclusion:
  putative_IRES
How IRES boundaries were determined:
experimentally_determined
The sequence of IRES region aligned to its secondary structure (if available):


Remarks:
GB virus A UTR (579 nt) and putative open reading frame (114 nt). The IRES activity was weak compared to HAV
IRES.
Citations:
Simons J. N., Desai S. M., Schultz D. E., Lemon S. M., Mushahwar I. K. (1996) Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization. J. Virol. 70(9):6126-6135
Last change to the database: 2015-04-16 16:45:23 GMT+1