The nucleic acid data:
IRESite Id: 41 Version: 10
Originaly submitted by: Václav Vopálenský Submission date: 2005-09-23 00:00:00
Reviewed by: Václav Vopálenský Last change: 2008-06-26 03:12:48
IRESite record type:
  natural_transcript
The shape of the nucleic acid molecule translated:
  linear
The quality of the mRNA/+RNA sequence:
  nonexisting_chimera_of_GenBank_record_and_tested_IRES_fragment
The abbreviated name of the virus/gene coding for this mRNA/+RNA molecule:
  GBV-C
The genetic origin of this natural mRNA/+RNA:
  viral
The GenBankId GI:# number of the most similar mRNA/+RNA sequence to this one.
1572849 
The mRNA/+RNA description: 
Hepatitis GB virus C polyprotein, partial cds.
The mRNA/+RNA sequence represented in the +DNA notation:


Credibility of mRNA sequence:
  guessed_as_the_sequence_was_never_published_by_authors_nor_described_in_sufficient_detail
The organism containing this mRNA with IRES segment in its genome:
Hepatitis GB virus C
A promoter reported in cDNA corresponding to IRES sequence:
  not tested
The total number of notable open-reading frames (ORFs):
  1
Notable Open-Reading Frames (ORFs; protein coding regions) in the mRNA/+RNA sequence:
ORF
ORF position:   1
Version: 3
Originaly submitted by: Václav Vopálenský Reviewed by: Václav Vopálenský
The abbreviated name of this ORF/gene:
GBV_C
The description of the protein encoded in this ORF:
Hepatitis GB virus C polyprotein.
The translational frameshift (ribosome slippage) involved:
  0
The ribosome read-through involved:
  no
The alternative forms of this protein occur by the alternative initiation of translation:
  no
The ORF absolute position (the base range includes START and STOP codons or their equivalents):
  535-9066
Remarks:
This sequence has been edited according to Figure 7 in cited article by curator. Monocistronic and bicistronic
T7 transcripts were tested in vitro in rabbit reticulocyte lysates. Please refer also to GI:1575393.
Citations:
Simons J. N., Desai S. M., Schultz D. E., Lemon S. M., Mushahwar I. K. (1996) Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization. J. Virol. 70(9):6126-6135
IRESs:
IRES:
Version: 8 Last change: 2007-05-15 00:00:00
Originaly submitted by: Václav Vopálenský Reviewed by: Václav Vopálenský
The IRES name:
  GBV-C
The IRES absolute position (the range includes START and STOP codons or their equivalents):
  13-642
Conclusion:
  putative_IRES
How IRES boundaries were determined:
experimentally_determined
The sequence of IRES region aligned to its secondary structure (if available):


Remarks:
GB virus C UTR (522 nt) and putative open reading frame (108 nt)
Citations:
Simons J. N., Desai S. M., Schultz D. E., Lemon S. M., Mushahwar I. K. (1996) Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization. J. Virol. 70(9):6126-6135
Last change to the database: 2015-04-16 16:45:23 GMT+1