The nucleic acid data:
IRESite Id: 435 Version: 0
Originaly submitted by: Martin Mokrejš
Reviewed by: Martin Mokrejš
IRESite record type:
  natural_transcript
The shape of the nucleic acid molecule translated:
  linear
The quality of the mRNA/+RNA sequence:
  our_best_guess
The abbreviated name of the virus/gene coding for this mRNA/+RNA molecule:
  REV-A
The genetic origin of this natural mRNA/+RNA:
  viral
The GenBankId GI:# number of exactly this mRNA/+RNA sequence:
88605102
The mRNA/+RNA description: 
Reticuloendotheliosis virus strain APC-566, complete genome.
The mRNA/+RNA sequence represented in the +DNA notation:


Credibility of mRNA sequence:
  end-to-end_sequence_reverse_engineered_and_should_match_experiment
The organism containing this mRNA with IRES segment in its genome:
Reticuloendotheliosis virus APC-566
A promoter reported in cDNA corresponding to IRES sequence:
  not tested
The total number of notable open-reading frames (ORFs):
  1
Notable Open-Reading Frames (ORFs; protein coding regions) in the mRNA/+RNA sequence:
ORF
ORF position:   1
Version: 0
Originaly submitted by: Martin Mokrejš Reviewed by: Martin Mokrejš
The abbreviated name of this ORF/gene:
gag-pol
The description of the protein encoded in this ORF:
gag-pol polyprotein
The translational frameshift (ribosome slippage) involved:
  0
The ribosome read-through involved:
  no
The alternative forms of this protein occur by the alternative initiation of translation:
  not tested
The ORF absolute position (the base range includes START and STOP codons or their equivalents):
  935-6016
Citations:
Lopez-Lastra M., Gabus C., Darlix J. L. (1997) Characterization of an internal ribosomal entry segment within the 5' leader of avian reticuloendotheliosis virus type A RNA and development of novel MLV-REV-based retroviral vectors. Hum. Gene Ther. 8(16):1855-1865
IRESs:
IRES:
Version: 1 Last change: 2008-06-26 01:28:45
Originaly submitted by: Martin Mokrejš Reviewed by: Martin Mokrejš
The IRES name:
  REV-A
The IRES absolute position (the range includes START and STOP codons or their equivalents):
  363-939
Conclusion:
  putative_IRES
How IRES boundaries were determined:
experimentally_determined
The sequence of IRES region aligned to its secondary structure (if available):


Remarks:
Sequence 2 from patent US 6783977 and JP 2001500021-A/2.
Citations:
Lopez-Lastra M., Gabus C., Darlix J. L. (1997) Characterization of an internal ribosomal entry segment within the 5' leader of avian reticuloendotheliosis virus type A RNA and development of novel MLV-REV-based retroviral vectors. Hum. Gene Ther. 8(16):1855-1865
Last change to the database: 2015-04-16 16:45:23 GMT+1