The description of the protein encoded in this ORF: cyclin-dependent kinase inhibitor 1B
The translational frameshift (ribosome slippage) involved: 0
The ribosome read-through involved: no
The alternative forms of this protein occur by the alternative initiation of translation: not tested
The ORF absolute position (the base range includes START and STOP codons or their equivalents): 466-1062
The sequence used in IRESite was obtained from IRESdb database to which it has been provided by S. Pyronnet.
Although the sequence appears to be an incomplete mRNA sequence when aligned to current GenBank RefSeq record
the base #1 of the query is the first base of the transcript as determined by primer extension (Minami et al.
>NM_004064.2 Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), mRNA
GENE ID: 1027 CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1)
[Homo sapiens] (Over 100 PubMed links)
Score = 281 bits (152), Expect = 2e-75
Identities = 154/155 (99%), Gaps = 0/155 (0%)
Query 1 GGGCCGTGGCTCGTCGGGGTCAGTGTCTTTTGGCTCCGAGGGCAGTCGCTGGGCTTCCGA 60
Sbjct 314 GGGCCGTGGCTCGTCGGGGTCTGTGTCTTTTGGCTCCGAGGGCAGTCGCTGGGCTTCCGA 373
Query 61 GAGGGGTTCGGGCCGCGTAGGGGCGCtttgttttgttcggttttgtttttttgAGAGTGC 120
Sbjct 374 GAGGGGTTCGGGCCGCGTAGGGGCGCTTTGTTTTGTTCGGTTTTGTTTTTTTGAGAGTGC 433
Query 121 GAGAGAGGCGGTCGTGCAGACCCGGGAGAAAGATG 155
Sbjct 434 GAGAGAGGCGGTCGTGCAGACCCGGGAGAAAGATG 468
The transcription start site of mouse p27kip1 is 23 bp upstream of the one from human (Minami et al. (1997),
A human sequence with just 153 bp long 5'-UTR is GI:9652559.