The nucleic acid data:
IRESite Id: 58 Version: 1
Originaly submitted by: Václav Vopálenský Submission date: 2005-07-30 00:00:00
Reviewed by: Václav Vopálenský Last change: 2006-04-28 00:00:00
IRESite record type:
  natural_transcript
The shape of the nucleic acid molecule translated:
  linear
The quality of the mRNA/+RNA sequence:
  both_UTRs_possibly_incomplete
The abbreviated name of the virus/gene coding for this mRNA/+RNA molecule:
  hSNM1
The genetic origin of this natural mRNA/+RNA:
  nuclear
The GenBankId GI:# number of exactly this mRNA/+RNA sequence:
577302
The mRNA/+RNA description: 
Homo sapiens KIAA0086 mRNA, partial cds.
The mRNA/+RNA sequence represented in the +DNA notation:


Credibility of mRNA sequence:
  guessed_as_the_sequence_was_never_published_by_authors_nor_described_in_sufficient_detail
The organism containing this mRNA with IRES segment in its genome:
Homo sapiens
A promoter reported in cDNA corresponding to IRES sequence:
  not tested
The total number of notable open-reading frames (ORFs):
  1
Notable Open-Reading Frames (ORFs; protein coding regions) in the mRNA/+RNA sequence:
ORF
ORF position:   1
Version: 0
Originaly submitted by: Václav Vopálenský Reviewed by: Václav Vopálenský
The abbreviated name of this ORF/gene:
hSNM1
The description of the protein encoded in this ORF:
The ha3611 gene product is related to S.cerevisiae SNM1 protein.
The translational frameshift (ribosome slippage) involved:
  0
The ribosome read-through involved:
  no
The alternative forms of this protein occur by the alternative initiation of translation:
  no
The ORF absolute position (the base range includes START and STOP codons or their equivalents):
  919-4041
OPTIONAL: The function of the encoded protein
Probably involved in DNA repair?
Remarks:
Start codon is not identified.
Citations:
Zhang X., Richie C., Legerski R. J. (2002) Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis. DNA Repair. 1(Amst):379-390
IRESs:
IRES:
Version: 4 Last change: 2007-01-23 00:00:00
Originaly submitted by: Václav Vopálenský Reviewed by: Václav Vopálenský
The IRES name:
  hSNM1
The IRES absolute position (the range includes START and STOP codons or their equivalents):
  1-918
Conclusion:
  putative_IRES
How IRES boundaries were determined:
guessed
The sequence of IRES region aligned to its secondary structure (if available):


Remarks:
IRES activity was shown in transiently transfected cells with bicistronic constructs.
Citations:
Zhang X., Richie C., Legerski R. J. (2002) Translation of hSNM1 is mediated by an internal ribosome entry site that upregulates expression during mitosis. DNA Repair. 1(Amst):379-390
Last change to the database: 2015-04-16 16:45:23 GMT+1