The nucleic acid data:
IRESite Id: 621 Version: 0
Originaly submitted by: Martin Mokrejš Submission date: 2009-08-29 20:30:39
Reviewed by: Martin Mokrejš
IRESite record type:
  natural_transcript
The shape of the nucleic acid molecule translated:
  linear
The quality of the mRNA/+RNA sequence:
  hopefully_full-length_mRNA
The abbreviated name of the virus/gene coding for this mRNA/+RNA molecule:
  DCV
The genetic origin of this natural mRNA/+RNA:
  viral
The GenBankId GI:# number of exactly this mRNA/+RNA sequence:
2388672
The mRNA/+RNA description: 
Drosophila C virus strain EB, complete genome.
The mRNA/+RNA sequence represented in the +DNA notation:


Credibility of mRNA sequence:
  unknown
The organism containing this mRNA with IRES segment in its genome:
Drosophila C virus EB
A promoter reported in cDNA corresponding to IRES sequence:
  not tested
The total number of notable open-reading frames (ORFs):
  2
Notable Open-Reading Frames (ORFs; protein coding regions) in the mRNA/+RNA sequence:
ORF
ORF position:   1
Version: 0
Originaly submitted by: Martin Mokrejš Reviewed by: Martin Mokrejš
The abbreviated name of this ORF/gene:
NS
The description of the protein encoded in this ORF:
non-structural polyprotein
The translational frameshift (ribosome slippage) involved:
  0
The ribosome read-through involved:
  no
The alternative forms of this protein occur by the alternative initiation of translation:
  not tested
The ORF absolute position (the base range includes START and STOP codons or their equivalents):
  799-6078
ORF
ORF position:   2
Version: 0
Originaly submitted by: Martin Mokrejš Reviewed by: Martin Mokrejš
The abbreviated name of this ORF/gene:
CP
The description of the protein encoded in this ORF:
capsid protein
The translational frameshift (ribosome slippage) involved:
  0
The ribosome read-through involved:
  no
The alternative forms of this protein occur by the alternative initiation of translation:
  not tested
The ORF absolute position (the base range includes START and STOP codons or their equivalents):
  6267-8972
Citations:
Johnson KN, Christian PD (1998) The novel genome organization of the insect picorna-like virus Drosophila C virus suggests this virus belongs to a previously undescribed virus family. J. Gen. Virol. 79(1):191-203
IRESs:
IRES:
Version: 2 Last change: 2009-08-31 00:56:27
Originaly submitted by: Martin Mokrejš Reviewed by: Martin Mokrejš
The IRES name:
  DCV_IGR
The IRES absolute position (the range includes START and STOP codons or their equivalents):
  6078-6266
Conclusion:
  putative_IRES
How IRES boundaries were determined:
guessed
The sequence of IRES region aligned to its secondary structure (if available):


Remarks:
Cherry et al. (2005) studied as 5NTR IRES region 1–796 and as IGR IRES region 6080–6282 of the genome.
The annotated IRES region was taken over from Nakashima and Uchiumi (2009) from Table 1.
Citations:
Nakashima N, Uchiumi T (2009) Functional analysis of structural motifs in dicistroviruses. Virus Res. 2(139):137-147
Cherry S, Doukas T, Armknecht S, Whelan S, Wang H, Sarnow P, Perrimon N (2005) Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes Dev. 19(4):445-452
Last change to the database: 2019-03-18 09:32:49 GMT+1